Question: Why Is Aspirin Combined With Clopidogrel?

How does aspirin and clopidogrel work?

It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent).

Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots..

Is clopidogrel stronger than aspirin?

In summary, clopidogrel appears to be somewhat more effective than aspirin if one is willing to accept the unitary atherosclerosis paradigm. The gain, however, is modest: about 200 patients should use clopidogrel rather than aspirin for 1 year to prevent just one vascular event.

What is the best time to take clopidogrel?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

What are the side effects of clopidogrel 75 mg?

Common side effects of clopidogrel can include:headaches or dizziness.nausea.diarrhoea or constipation.indigestion (dyspepsia)stomach ache or abdominal pain.nosebleeds.increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

Can I drink coffee with clopidogrel?

Conclusions: Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

Can I take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

Can you take aspirin and clopidogrel together?

Do not take aspirin for pain relief (300mg tablets) or ibuprofen while you’re taking clopidogrel, unless a doctor has said it’s OK. They increase the chance of bleeding. You can take paracetamol together with clopidogrel.

Are aspirin and clopidogrel the same?

Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Aspirin and Plavix belong to different drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID). Aspirin also is used to reduce fever, and to treat pain and inflammation in the body.

What medications interact with clopidogrel?

Serious InteractionsSELECTED PLATELET AGGREGATION INHIBITORS/NSAIDS.CLOPIDOGREL/ESOMEPRAZOLE; OMEPRAZOLE; CIMETIDINE.CLOPIDOGREL/FLUCONAZOLE; KETOCONAZOLE; VORICONAZOLE.CLOPIDOGREL/ETRAVIRINE.CLOPIDOGREL/FELBAMATE.CLOPIDOGREL/TICLOPIDINE.CLOPIDOGREL/FLUOXETINE; FLUVOXAMINE.More items…

What foods should you avoid if you are on blood thinners?

While eating small amounts of foods that are rich in vitamin K shouldn’t cause a problem, avoid consuming large amounts of certain foods or drinks, including: Kale. Spinach. Brussels sprouts.

Does clopidogrel affect the kidneys?

Conclusions. In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.