Quick Answer: What Is The Best PPI To Take With Clopidogrel?

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP)..

What is the safest drug for acid reflux?

At this point, if you are concerned about taking Zantac there are alternative medications that are perfectly acceptable. Pepcid and Tagamet are both over the counter histamine blockers that can be used in place of Zantac.

Can omeprazole and Plavix be taken together?

FDA is recommending that the co-administration of clopidogrel (Plavix), a drug used to prevent blood clot formation, and omeprazole (Prilosec/Prilosec OTC), a proton pump inhibitor (PPI) used to reduce stomach acid, be avoided because omeprazole reduces the effectiveness of clopidogrel.

Can pantoprazole be taken with clopidogrel?

clopidogrel pantoprazole Combining these medications may reduce the effectiveness of clopidogrel in preventing heart attack or stroke. The interaction is most likely to occur if you are using a higher dosage of pantoprazole than recommended or if you are using it too frequently.

Do you need PPI cover with clopidogrel?

In light of the most recent evidence, the previous advice (to avoid all PPIs unless absolutely necessary for patients taking clopidogrel) is no longer considered necessary. Nevertheless, as a precaution, concomitant use of clopidogrel with omeprazole or esomeprazole should be discouraged.

Which is the safest proton pump inhibitor?

Pantoprazole is marketed as being cheaper, and may be better for patients paying for their own medications. Esomeprazole (Nexium), a new and very potent PPI, was approved by the U.S. Food and Drug Administration (FDA) in 2001. Zegerid is a combination of omeprazole and sodium bicarbonate.

What foods neutralize stomach acid?

Foods That Help Prevent Acid RefluxHigh-fiber foods. Fibrous foods make you feel full so you’re less likely to overeat, which may contribute to heartburn. … Alkaline foods. Foods fall somewhere along the pH scale (an indicator of acid levels). … Watery foods. … Milk. … Ginger. … Apple cider vinegar. … Lemon water.

How do I stop taking proton pump inhibitors?

Folks who have been taking PPIs for a period of six months might consider tapering down their dose instead of stopping cold turkey. However, you might be wondering how to properly taper down. Try to reduce your dose by 50% every week. Once you are on the lowest dose for one full week, you can try stopping your PPI.

What foods should I avoid when taking clopidogrel?

There’s a risk that you could get a stomach ulcer. Is there any food or drink I need to avoid? Do not drink grapefruit juice while taking clopidogrel. Grapefruit juice may increase the blood-thinning effect of your medicine.

When should I take proton pump inhibitors?

Commonly, these medicines are taken 30 minutes before the first meal of the day. You can buy some brands of PPIs at the store without a prescription. Talk to your health care provider if you find you have to take these medicines on most days. Some people who have acid reflux may need to take PPIs every day.

Which PPI is safe with clopidogrel?

Accordingly, some studies showed that omeprazole attenuates the antiplatelet effect of clopidogrel[13-15] but others did not confirm these findings[19,20]. In contrast, esomeprazole, lansoprazole, pantoprazole and rabeprazole did not affect platelet function in patients treated with clopidogrel[13,15,19-22].

Is it OK to take lansoprazole with clopidogrel?

lansoprazole clopidogrel Combining these medications may reduce the effectiveness of clopidogrel in preventing heart attack or stroke. The interaction is most likely to occur if you are using a higher dosage of lansoprazole than recommended or if you are using it too frequently.